Characterization of Broadly Neutralizing Antibodies to PRRSV

This week, Dr. Jordan Young from the late Dr. Murtaugh‘s lab shares his latest research project regarding the immune response against PRRS.

Key point

  • PRRSV antibodies were determined to be broadly binding, but only homologously neutralizing, suggesting a polyclonal response, involving multiple PRRSV specific antibodies might be necessary for PRRSV neutralization.
  • This means that vaccinations aiming to protect from infection likely need to involve exposure to multiple strains of PRRSV to induce a broad protective immunity, rather than relying on single-strain vaccines.
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