Can 2 strains of PRRSv be highly homologous but have distinct virulence?

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

Key points

  • Two novel HP-PRRSV variants (XJ17-5 and JSTZ1712-12) that have the new genetic feature of 150-amino-acid deletion in nsp2 were identified.
  • Even though XJ17-5 and JSTZ1712-12 isolates share high genomic homology, they had distinct pathogenicity for piglets.
  • Fragment comparisons identified 34 amino acid differences between the two isolates which might be related to distinct virulence.
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Best of Leman 2019 #1: D. Olsen – Batch farrowing in large farms

This is a favorite on the blog. Once a month, we are sharing with you a presentation given at the Allen D. Leman swine conference, on topics that the swine group found interesting, innovative or that lead to great discussions.

We can find all of the presentations selected from the previous years’ conferences on the blog here.

We are kicking off this series with a presentation from Dr. Daryl Olsen from AMVC regarding batch farrowing in large farms and the reasons why you may want to implement it. We hope you enjoy it!

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PRRSV 1-7-4 ORF5 diversity over time

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

This week, the MSHMP team is looking at 16 years of genetic diversity of ORF-5 from the PRRS virus sequences submitted by the MSHMP participants

Key Points

  • PRRSV ORF5 sequence monitoring over time contributes to the understanding of pathogen evolution.  
  • Range of PRRSV 1-7-4 percent divergence has decreased over the last 16 years between 2003 and 2019, which is consistent with lineage turnover previously described.
  • PRRSV 1-7-4 can belong to a specific lineage or sublineage, 1A being the most common currently.
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New training videos available: protecting pigs and people from the flu and moving sows

Drs. Jeff Bender and Cesar Corzo collaborated with the Upper Midwest Agricultural Safety and Health Center and the National Pork Board to develop training videos for anyone interacting with pigs.

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Role of stress on early pathogenesis of Senecavirus A in pigs

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

This week, Dr. Guilherme Preis, phD candidate with Dr. Fabio Vannucci shares results of his latest research on stress and its influence on Senecavirus A.

Key points

  • Impact of a stress model on the early pathogenesis of Senecavirus A was evaluated.
  • Time to detect replicating virus in snout skins and coronary bands was 48 hours post inoculation.
  • Naïve animals likely do not have enough time to develop vesicles during most transportation events, if exposed via the nasal route.
Continue reading “Role of stress on early pathogenesis of Senecavirus A in pigs”