Phylogenetic Structure and Sequential Dominance of Sub-Lineages of PRRSV Type-2 Lineage 1 in the United States

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

Keypoints

  • Lineage 1 PRRSv, the most prevalent PRRSV lineage in the U.S, can be sub-divided into eight sub-lineages
  • We documented the cyclic emergence and turnover of different lineages and sub-lineages (about every 3 years) based on both sequence count data and estimated past viral population sizes inferred from genetic diversity through time.
  • The eight sub-lineages differed in key GP5 amino acid sites that are thought to be involved in the immune response to the virus.
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Join the team! Public health position available at the UMN CVM

The University of Minnesota, Veterinary Population Medicine Department (VPM), College of Veterinary Medicine (CVM) is seeking to hire an outstanding candidate for a 100% Assistant/Associate/Full Professor (contract) position in the area of Veterinary Public Health. Learn more about the position.

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MSHMP data collection update 2020-2021

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

Reaching the end of the fiscal year, we wanted to report an update on the magnitude of the MSHMP project by describing the data collected and maintained in the MSHMP database that is used to create our reports and to analyze industry related questions and trends.

Breakdown of MSHMP Participants: 37 separate systems made up of 3 regional projects and 31 Production companies and veterinary clinics. Three companies are represented by multiple MSHMP systems due to geographic and management considerations. 

There are a total of 2,073 farms within the program, 1,168 breeding herds, 872 growing pig farms and 30 boar studs. The total number of sows monitored in our project is 3,503,287 sows (>3.5 million sows)

The average number of breeding herd per system is 32 (min of 5 and max of 239) with the 50% of the systems having 18 farms or more.

The mean inventory per farm by system (excluding finisher farms) was 2916 sows (ranging those means from 700-6500). Figure 1 shows farm’s average inventory distribution per participant system.

Different production types are recorded with 56% of breeding herds, and 38% represented by wean to finish and finisher farms from four participant systems (Table1). 

Approximately 20 % of the sow farms are filtered, with 50 being not filtered, 27 partially filtered (filtered only during certain months of the year), and 167 filtered year-round. We are collecting information on the type of filtration system (i.e. positive/negative). Approximately 20% of the farms have reported it, with most of them using positive filtration. 

At MSHMP we are currently collecting status for three pathogens causing important impact to the industry. Over the 2020-2021 year, 1056, 1176, and 1170 farms reported status for PRRS, PED, and PDCoV respectively. Farm status regarding Mycoplasma was recorded for eight production systems, comprising 106 sow farms.

We would like to thank all MSHMP participants for the willingness to share your information. Without their contributions, we could not generate these summaries.

DVM students, 1 week left to participate in the Morrison Swine Innovator Prize!

Veterinary student, did you shadow a swine practitioner this summer or were involved in an interesting clinical case investigation? Did you work on your veterinary skills by designing a differential diagnosis list or working on a treatment plan? Did you investigate a problem by analyzing production records? Share your work at the Allen D. Leman Swine Conference to win the Morrison Swine Innovator Prize!

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Evaluation of oral fluid as an aggregate sample for early detection of ASF

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

Since ASF has been found in the Dominic Republic last week, swine producers are concerned about it spreading into the United States. Early detection would be essential to ensure a rapid response and containment of the disease. This week, the MSHMP team shares the summary of a Canadian study looking at using oral fluids as a tool to diagnose ASF.

Key Points

  • Oral fluid samples may be used as a low labor, cost effective alternative sample source for rapid detection of ASFV during ASF surveillance.
  • ASFv genome was detected in oral fluids at low-to-moderate levels as early as 3-5 days post infection, before clinical symptoms started. 
  • Further research is needed to understand limitations and best practices of oral fluid sampling for ASFv
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