Exploring heterologous prime-boost vaccination approaches to enhance influenza control in pigs

Chong Li and colleagues from the University of Minnesota provide new insights for the potential use of the heterologous prime-boost vaccination strategy to control swine infuenza A virus (IAV) infection in pigs by bringing us a research article published in Veterinary Research.

Highlights

  • Heterologous prime-boost vaccination has the potential to deal with diverse IAV infection in multiple animal models.
  • Pigs in the heterologous prime-boost vaccination group had more favorable outcomes consistent with a better response against virus challenge (H1N1 and H3N2 IAV) than non-vaccinated pigs.
  • Similarly, a multivalent heterologous inactivated vaccine boost to pigs following a single live attenuated IAV vaccine (LAIV) administration was also beneficial.
  • More studies are still needed to validate the concept of heterologous prime-boost to control IAV under feld conditions.
Continue reading “Exploring heterologous prime-boost vaccination approaches to enhance influenza control in pigs”

Best of Leman #7: M. Ellis – Managing Piglet Preweaning Mortality

This is our most popular series on the blog. Once a month, we are sharing with you a presentation given at the Allen D. Leman swine conference, on topics that the swine group found interesting, innovative or that lead to great discussions.

We can find all of the presentations selected from previous conferences on the blog here.

Today, we look back at one of the keynote presentations of the 2019 Allen D. Leman conference. Dr. Mike Ellis from the University of Illinois explains why we should not dismiss pre-weaning mortality and what strategies can be used to mitigate it.

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Molecular detection of Porcine Reproductive and Respiratory Syndrome virus, Porcine Circovirus 2 and Hepatitis E virus in oral fluid compared to their detection in feces and serum

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

Doctors Plut, Kamnikar-Ciglenecki and Stukeli from the University of Ljubljana (Slovenia) highlight the usefulness of pig oral fluid (OF) to detect Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), Porcine Circovirus Type 2 (PCV2) and Hepatitis E virus (HEV) in different pig age categories. Read here the full article published in BMC Veterinary Research.

Key Points

  • OF, feces and serum were evaluated for the detection of PRRSV, PCV2 and HEV in six farms.
  • OF samples had good agreement with serum sample PCR results for the detection of all three viruses.
  • The study highlights that pooled samples can potentially be used to investigate viral presence on farms.
Continue reading “Molecular detection of Porcine Reproductive and Respiratory Syndrome virus, Porcine Circovirus 2 and Hepatitis E virus in oral fluid compared to their detection in feces and serum”

2020 Allen D Leman Swine Conference goes VIRTUAL!

Same great dates… September 19-22, 2020

Same great content…science-driven solutions to the complex challenges facing the global swine industry.

New great format… VIRTUAL!

Follow this link for more information!

https://ccaps.umn.edu/allen-d-leman-swine-conference

Senecavirus A in processing fluids during an outbreak of SVA – a call for study participation!

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

Doctors Guilherme Preis and Cesar Corzo from the University of Minnesota share with us preliminary data from a Senecavirus A (SVA) outbreak investigation in a sow herd. This research emphasizes the importance of understanding the within-herd epidemiology of this virus.

Highlights

  • SVA is still present in the U.S. swine herds at lower levels.
  • SVA RNA has been consistently detected in processing fluids in the event of a disease outbreak in a sow herd.
  • Viral dynamics and shedding cessation in the breeding herds need to be better characterized.
Continue reading “Senecavirus A in processing fluids during an outbreak of SVA – a call for study participation!”