Phylogenetic Lineages of Canadian PRRSV-2 Reveal Transboundary Spread and Two Novel Sub-Lineages

Today we are sharing a recent publication from the VanderWaal lab looking at PRRSV sequences from Canada. The full publication is available in open access on the journal Pathogens’ website.

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In vitro evaluation of PRRSV ORF5 sequences in samples containing PRRSV modified-live vaccine and wild-type strains

Today, we are sharing a publication from recent PhD graduate Joaquin Alvarez Norambuena in collaboration with the VDL and the MSHMP team in the Journal of Veterinary Diagnostic Investigation. In this paper, Dr. Alvarez Norambuena explores how Sanger sequencing performs when testing samples with multiple PRRS strains.

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Tracking between-farm PRRSV-2 transmission and its potential routes through the virus genetic relationship and farm-based data

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

In this week’s Science Page University of Minnesota researchers Nakarin Pamornchainavakul, Dennis N. Makau, Igor A. D. Paploski, Cesar A. Corzo and Kimberly VanderWaal take a look at the spread of different variants of PRRS between farms.

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Infection dynamics and incidence of wild-type PRRS virus in growing pigs

This new publication from the Torremorell’s lab is focusing on growing pig herds in the Midwest and how wild-type PRRS virus can spread among them. The full publication is available on the journal’s website.

Highlights

  • Wild-type PRRSV infections in growing pigs are common and more prevalent towards the middle to end of the growing phase.
  • Site-level surveillance is useful to understand PRRSV infections in vaccinated pigs.
  • Biosecurity practices in growing pig sites are key to prevent lateral infections.
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Understanding whether PRRS viruses in a neighborhood are closely related

This week, the MSHMP team is sharing results from a study looking at how related PRRSv ORF5 sequences from a same area are.

Key Points

  • 28 space-time clustering of PRRSv based on producers’ routine molecular surveillance were identified in the course of 2010-2019.
  • Being inside or outside a space-time cluster significantly explains the genetic variability of most, but not all cases.
  • Assessing space, time, and genetic relatedness relationships in PRRSV transmission is complex, and overall trends might miss important case information.
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