Effect of Killed PRRSV Vaccine on Gut Microbiota Diversity in Pigs

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

Researchers Fangfeng Yuan, Jaishree Sharma, Som G. Nanjappa, Christopher A. Gaulke, and Ying Fang from the University of Illinois at Urbana Champaign present information on the impact of killed PRRSV vaccine on the gut microbiome in today’s Science Page.

Continue reading “Effect of Killed PRRSV Vaccine on Gut Microbiota Diversity in Pigs”

Best of Leman 2018 series #10: A. Gomez – Swine gut microbiome studies, where are we at?

Our tenth presentation is from Dr. Andres Gomez, from the College of Food, Agricultural and Natural resource Sciences (CFANS) regarding the latest development in the swine gut microbiome studies.

Continue reading “Best of Leman 2018 series #10: A. Gomez – Swine gut microbiome studies, where are we at?”

Metabolites, antibiotimicrobials, and gut microbiome

Salmonella Bacteria, Source: NIAID

In this article published by the National Hog Farmer, nutritionists and microbiome analysts from the University of Minnesota discuss what consequences antimicrobials can have on the gut microbiome.

What does microbiome mean?

Microbiome refers to all of the microbes present in an area. For example, gut microbiome is the entire population of microorganisms (most of the time bacteria) present in the intestinal tract.

The purpose of this research program is to study the effects antimicrobials can have on the bacterial populations present in the gut and how those changes influence the metabolites present in the pig.

What is a metabolite?

Metabolites are usually small molecules and are created by enzymatic reactions happening through the natural life of a cell or organism.

One of the effects of administering tylosin to pigs was the increased growth of bacteria producing short-chain fatty acids in the intestinal flora. The use of this antimicrobial also led to the development of Lactobacillus in the gut.

Relating changes in metabolites to the gut microbiome allows for a more complete understanding and investigation of the impact that antibiotics have in enhancing growth. Without completely understanding the mechanism of increased growth, antibiotic alternatives could be used inappropriately without much added benefit.

Link to the full paper