This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.
This week, we are sharing a report by the MycoLab regarding piglet microbiota and its potential influence of M.hyopneumoniae susceptibility.
Key points
Early life gut microbiota could be a potential determinant in modulating susceptibility to chronic respiratory diseases such as enzootic pneumonia in pigs.
Increased abundance of short‐chain fatty acid producing bacteria in piglet gut was associated with decreased M. hyopneumoniae respiratory lesions.
Understanding the function and composition of a ‘healthy’ pig gut microbiota would aid to successfully implement novel disease control strategies.
Podcasts are a perfect way to get caught up with new swine information! We are presenting you the latest episode from “At The Meeting… Honoring Dr. Bob Morrison” in collaboration with SwineCast.
This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.
Due to the nature of microbiome it cannot be studied separated from other relevant information and should be studied together with metabolomics, genomics, immunity and nutrition.
Development of models at different levels are needed to evaluate the effect on microbiome of different strategies and to evaluate the impact of microbiome changes on the pig gut health.
This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.
Microbiome and more specifically the bacteria residing in the gut play multiple roles related with nutrition and health.
The study of swine gut bacteria is still in its early stages, and the field contains many possibilities exciting possibilities.
Funding and microbiome classification are two of the most important barriers to overcome in order to gain insight into the complex field of swine gut bacteria.
This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.
This week, we are sharing the summary of a publication by Dr. Fernando Leite who recently received his PhD from the University of Minnesota. The full scientific article regarding the effect of the vaccination against Lawsonia intracellularis on the shedding of Salmonella typhimurium and the host microbiome is available on open access in Nature.
Materials and Methods
A total of five treatment groups were used:
challenged with S. Typhimurium alone,
challenged with both S. Typhimurium and L. intracellularis,
challenged with S. Typhimurium and vaccinated against L. intracellularis,
challenged with both S. Typhimurium and L. intracellularis and vaccinated against L. intracellularis
a non-infected control.
Results
The greatest difference in shedding level between groups was found at 7 days post-infection. At this time point, the co-challenged animals from the vaccinated group shed statistically less S. Typhimurium per gram of feces than the animals from the non-vaccinated, co-challenged group. The co-challenged vaccinated group also shed significantly less S. Typhimurium than the singly infected S. Typhimurium group.
L. intracellularis vaccination did not have a significant impact on S. Typhimurium shedding when animals were singly infected with S. Typhimurium.
At 7 days post-infection, different treatment groups had significant differences in their microbiome community structure. The co-infected vaccinated group clustered apart from all other treatment groups.
Conclusion
These results indicate that vaccination against L. intracellularis impacts the microbiome and reduces shedding of S. Typhimurium in co-infected animals.
