Summary: The impacts of viral infection and subsequent antimicrobials on the microbiome-resistome of growing pigs

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

The Science Page this week describes a study done by Tara N. Gaire, Carissa Odland, Bingzhou Zhang, Tui Ray, Enrique Doster, Joel Nerem, Scott Dee, Peter Davies and Noelle Noyes and sheds some light on the antimicrobial resistances carried by the pig’s microbiome after disease and treatment.

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Summary: Evaluation of the Impact of Antimicrobial Use Protocols in Porcine Reproductive and Respiratory Syndrome Virus-Infected Swine on Phenotypic Antimicrobial Resistance Patterns

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

Today, researchers Carissa A. Odland, Roy Edler, Noelle R. Noyes, Scott A. Dee, and Joel Nerem summarize the findings of a 149-day study on antimicrobial use during PRRS infections.

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Summary of: Antimicrobial use in lactating sows, piglets, nursery, and grower-finisher pigs on swine farms in Ontario, Canada during 2017-2018

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

This week’s science page is a summary of a research project done by Angelina L. Bosman, Anne E. Deckert, Carolee A. Carson, Zvonimir Poljak, Richard J. Reid-Smith, and Scott A. McEwen at the University of Guelph and the Public Health Agency of Canada.

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Antimicrobial use, PRRS, and the microbiome with McKnight Land-Grant Professor Noelle Noyes

Dr. Noelle Noyes received the 2022 McKnight Land-Grant Professorship for her work on Microbes for Sustainable Intensification of Livestock Production. As the human population expands, so does its demand for protein. Livestock farmers must meet this demand, but their land and water are shrinking rapidly, meaning they must produce more with less. Dr. Noyes confronts this challenge through scientific discovery of the livestock microbiome.

Noyes receives 2022 McKnight Land-Grant Professorship

In one of their latest studies in collaboration with Pipestone Systems and Dr. Peter Davies, the Noyes lab evaluates the impact of antimicrobial use on resistance patterns in PRRS-infected pigs. The publication is available in open access in the Applied and Environmental Microbiology journal.

Despite a recognized need for more longitudinal studies to assess the effects of antimicrobial use on resistance in food animals, they remain sparse in the literature, and most longitudinal studies of pigs have been observational. The current experimental study had the advantages of greater control of potential confounding, precise measurement of antimicrobial exposures which differed markedly between groups and tracking of pigs until market age. Overall, resistance patterns were remarkably stable between the treatment groups over time, and the differences observed could not be readily reconciled with the antimicrobial exposures, indicating the likely importance of other determinants of antimicrobial resistance at the population level.

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Dr. Ilya Slizovskiy receives new USDA-FSIS fellowship

Dr. Ilya Slizovskiy, PhD student in the Noyes lab, is the first recipient of a new fellowship created by the Food Safety Inspection Service, FSIS.  This competitive fellowship is committed to data-driven and science-based approaches applied to all aspects of FSIS public health mission. Slizovskiy’s project focuses on new techniques to detect antimicrobial resistances and foodborne pathogens.

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