Podcasts are a perfect way to get caught up with new swine information! We are presenting you the latest episode from “At The Meeting… Honoring Dr. Bob Morrison” in collaboration with SwineCast.
In this episode of At the Meeting honoring Dr. Bob Morrison, we share a conversation on porcine circovirus 3, or PCV3.
Dr. Montse Torremorell joins Dr. Tom Wetzel and Dr. Gordon Spronk with special guest Dr. Darin Madson, Iowa State University, to talk about porcine circovirus 3 and how it is both similar to, and different from PCV2.
Dr. Madson and the show’s cohosts discuss clinical signs associated with PCV3, including myocarditis, respiratory issues, and reproductive problems, as well as how current research is focused on better understanding the virus, its history, and whether any current PCV vaccines could offer some form of cross-protection.
Abortion cases in the study had a high rate of PCV3 positivity.
PCV3 found in association with lesions in an abortion case suggesting causality.
The study looked at 730 cases from the UMN Veterinary Diagnostic Laboratory with a positive sample for PCV3, received between Feb 2016 and Jan 2018.
Out of 22 states, 18 states were PCV3 positive. PCV3 was detected in pigs from all ages.
The positive rate among fetus, piglets, nursery and finishing pigs ranged from 15% to 20%. The PCV3 rate in adults was 35%.
PCV3/PCV2 co-infection rate was 5.2%, and PCV3/PRRSV coͲinfection rate was 7.6%.
In our data, we had 67 abortion cases, and 40% of them were PCV3 positive. In one abortion case investigation, histological lesions were observed in lung tissue of aborted fetus and PCV3 in-situ hybridization showed presence of PCV3 in the lesion.
Seven PCV3 whole genome sequences were obtained. Current PCV3 genomes in the U.S shared over 98% nucleotide identities. U.S strains did not cluster together and were grouped with PCV3 sequences obtained in other countries.