Transmission of a live influenza A virus vaccine in commercial pre-weaned pigs

The Plos One journal just published a new study by Dr. Gustavo Lopez and the Torremorell lab. The objectives of the project were to  1)assess the onset and duration of live attenuated influenza vaccine shedding in vaccinated pre-weaned pigs, 2)investigate the transmission of the live attenuated influenza vaccine from vaccinated to non-vaccinated pigs under field conditions and 3)evaluate whether the live attenuated influenza vaccine could be aerosolized and detected in the environment.

Continue reading “Transmission of a live influenza A virus vaccine in commercial pre-weaned pigs”

Multiple vaccinations: what effect on M. hyopneumoniae infection?

Dr. Betlach and the team from the MycoLab recently published a study in the journal Vaccine, regarding the impact of multiple vaccines against Mycoplasma hyopneumoniae. They assessed bacterial load and protection against infection in gilts.

Highlights

  • Vaccination against M. hyopneumoniae reduced bacterial load in infected gilts.
  • Vaccination of both infected and contact gilts reduced M. hyopneumoniae transmission.
  • Genetic diversity of M. hyopneumoniae was not influenced by vaccination.
Continue reading “Multiple vaccinations: what effect on M. hyopneumoniae infection?”

Natural transmission and detection of Mycoplasma hyopneumoniae in a naïve gilt population

Dr. Alyssa Betlach, member of the Maria Pieters Myco Lab, recently published a study on the natural transmission of Mycoplasma hyopneumoniae in Veterinary Microbiology. The study evaluated transmission rate in a naïve gilt population and compared various sample types to detect infection.

Continue reading “Natural transmission and detection of Mycoplasma hyopneumoniae in a naïve gilt population”

Dr. Igor Paploski in the top 10 UMN Research Day infographics

Dr. Igor Paploski, postdoctoral associate from the VanderWaal lab ranked in the top 10 infographics at the University of Minnesota Research Day for his latest research on transmission of swine infectious diseases.

Continue reading “Dr. Igor Paploski in the top 10 UMN Research Day infographics”

Contrasting animal movement and spatial connectivity networks in shaping transmission pathways of a genetically diverse virus

Researchers VanderWaal, Paploski, Makau and Corzo at the University of Minnesota provide new insights into how PRRSv spreads between farms and the importance of data sharing in this research article published in Preventive Veterinary Medicine.

Highlights

  • The study combined three years of PRRSv genetic data with network analysis to look at the dynamics of between-farm spread of PRRSv.
  • Data from a subset of the MSHMP farms was used and included farm location, animal movements between farms, and any PRRSv sequence recovered those farms.
  • The researchers identified between-farm infection chains and elucidated types of contact that were most associated with PRRSv transmission.
  • Results showed that animal movements, not local area spread, play a dominant role in shaping transmission pathways.
  • Local area spread ( within a 5 km area) also contributed to the PRRSv transmission pathway, though to a much lesser extent than animal movements.

Implications for COVID-19?

Molecular geneticists and epidemiologists perform similar work for the human population, especially now during the COVID-19 pandemic.  Follow this link to learn how researchers trace the routes the virus has traveled across the world in an attempt to find out how quickly and easily SARS-CoV-2 spreads using globally shared data.

Continue reading “Contrasting animal movement and spatial connectivity networks in shaping transmission pathways of a genetically diverse virus”