Senecavirus A in processing fluids during an outbreak of SVA – a call for study participation!

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

Doctors Guilherme Preis and Cesar Corzo from the University of Minnesota share with us preliminary data from a Senecavirus A (SVA) outbreak investigation in a sow herd. This research emphasizes the importance of understanding the within-herd epidemiology of this virus.

Highlights

  • SVA is still present in the U.S. swine herds at lower levels.
  • SVA RNA has been consistently detected in processing fluids in the event of a disease outbreak in a sow herd.
  • Viral dynamics and shedding cessation in the breeding herds need to be better characterized.
Continue reading “Senecavirus A in processing fluids during an outbreak of SVA – a call for study participation!”

Senecavirus A continues to be present in the United States swine herd

This week, Dr. Guilherme Preis, graduate student at the University of Minnesota with Drs. Corzo and Vannucci is sharing an update on the prevalence of Senecavirus A in the United States.

Key Points

  • Senecavirus A continues to present in the US at low levels. 
  • Sow herds are more likely to test positive than growing pig herds. 
  • SVA positive herds tend to have a large number of positive samples. 
Continue reading “Senecavirus A continues to be present in the United States swine herd”

Role of stress on early pathogenesis of Senecavirus A in pigs

This week, Dr. Guilherme Preis, phD candidate with Dr. Fabio Vannucci shares results of his latest research on stress and its influence on Senecavirus A.

Key points

  • Impact of a stress model on the early pathogenesis of Senecavirus A was evaluated.
  • Time to detect replicating virus in snout skins and coronary bands was 48 hours post inoculation.
  • Naïve animals likely do not have enough time to develop vesicles during most transportation events, if exposed via the nasal route.
Continue reading “Role of stress on early pathogenesis of Senecavirus A in pigs”

Shedding light on the epidemiology of Senecavirus A

PhD-candidate Guilherme Milanez Preis, working with Drs. Cesar Corzo and Fabio Vannucci on the epidemiology of Senecavirus A. In an article for the National Hog Farmer, Preis shares the latest results of his work on Senecavirus A prevalence in the USA.

Continue reading “Shedding light on the epidemiology of Senecavirus A”

Science Page: Natural and experimentally-induced Senecavirus A infections in boars

This is our Friday rubric: every week a new Science Page from the Bob Morrison’s Swine Health Monitoring Project. The previous editions of the science page are available on our website.

This week, we are sharing a study from Dr. Matt Sturos from the University of Minnesota, Veterinary Diagnostic Laboratory regarding Senecavirus A in boars.

Key points

  • Naturally-infected boars have been documented to shed Senecavirus A (SVA) RNA in semen for up to three months after exhibiting vesicular disease.
  • Experimentally-infected boars shed SVA RNA in semen for up to three weeks post-inoculation.
  • The majority of experimentally-infected boars did not exhibit clinical signs or develop apparent lesions.

Senecavirus A in boars
Testis of boar naturally-infected with Senecavirus A. Bright red areas indicate positive signal for SVA by in-situ hybridization.

“This update shows that SVA RNA is shed in semen from both naturally-infected and experimentally-inoculated boars. The prolonged shedding of viral RNA in semen and the presence of SVA RNA in the testes and tonsils of the naturally-infected boars for up to three months are concerning findings and raises the possibility of persistent infection in boars. While the duration of shedding in semen for the experimentally-infected boars was considerably shorter than for the naturally-infected boars, the fact that all contemporary-strain boars had PCR-positive semen on at least one collection indicate that shedding in semen is a repeatable phenomenon and shedding occurred in some boars which did not exhibit clinical signs or develop vesicular lesions. It is currently unknown whether semen from infected boars can serve as a source of infection if used to inseminate susceptible females.”