Production impacts of PRRSV-2 1C.5.32 and other variants (1A.2, 1H.18): Call for participants

The University of Minnesota Swine Group is seeking sow farms and grow-finish farms that have recently broken with PRRSV-2 variant 1C.5.32,  variant 1A.2, or 1H.18 to contribute to a research study on PRRSV-2 virulence.  This study addresses the virulence and production impacts of a novel PRRSV-2 variant, denoted as 1C.5.32, which began spreading rapidly in the Midwest in late 2024. We aim to quantify this new variant’s virulence and production impacts in sow farms and nursery-age pigs in comparison to other prevalent variants (1A.2 and 1H.18), and quantify the role of co-infections in shaping PRRSV severity.

Eligibility:

  • Sow farms and grow-finish farms with recent PRRSV-2 outbreaks associated with 1C.5.32, 1A.2, or 1H.18.
  • Willingness to share production records, especially related to mortality, morbidity, vaccination history, and interventions from ~5 months prior to outbreak onset through ~5 months post-outbreak
  • Located within 4 hours of Twin Cities (or willingness of field veterinarian to collect and send samples to UMN).

Farm sampling:

Sow farm sampling: 30 serum samples from piglets from each farm near the onset (~week 3-4) of the PRRSV-2 outbreak. If a sow farm remains PRRSV-positive four months later, an additional set of samples from 30 additional piglets will be requested from the farm. 

Nursery-aged pig sampling:  30 serum samples from nursery-age pigs from each farm ~6-8 weeks post-placement (sow farm PRRSV-2 positive with a variant of interest). The samples will include blood/serum samples from individual pig, as well as oral fluid samples from ropes. 

If you are interested in participating or have questions about eligibility, please contact Dr. Kim VanderWaal (kvw@umn.edu) or Dr. Mariana Kikuti (mkikuti@umn.edu).  

This study is funded by the University of Minnesota Rapid Agricultural Response Fund.

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